Cell Division

Am I out of my head?

Am I out of my mind?

If you only knew the bad things I like

Don't think that I can explain it

Suppressor genes say, it's complicated

Don't matter what Rb says

Don't matter what P-five-three do

I only wanna do bad things to you

So good, that APC can't stop it

What can I say, it's complicated

You activate Bax

When DNA ain’t good

Promote cell death

Healthy cells in the hood

P to the five three

You’re what I need

You make sure

My cell cycle ain’t ever be freed

Cdk inhibitor p21

You make me stay in G1

Inhibit transcription of Akt

Apoptosis the enemy

You keep me in check with those hips

The shape of your activated tips

While your body's giving me life

Until you’re degraded and dismissed

Then cancer came

I want p53 forever

only if you don’t function

Mutant in my genome, I can inhibit p21 whenever like,

I want you forever

Only if you don’t function

Mutant in my genome, I can proliferate wherever now

Am I out of my head?

Am I out of my mind?

If you only knew the bad things I like

Don't think that I can explain it

Suppressor genes say, it's complicated

Don't matter what Rb says

Don't matter what P-five-three do

I only wanna do bad things to you

So good, that APC can't stop it

What can I say, it's complicated

Adenomatous

Polyposis coli

It inactivates

beta-catenin

And wnt pathway

And proliferation

And’s tumor suppressor

Loss of function makes tumor cells

Knock me down to epithelial cells

I got what you dream about

Uncontrolled cell dividing and growth

Rapid mutation accumulate out

And you then mutate the oncogene Ras

While another suppressor got killed

While p53’s giving it up

And you metastasis and invade

Then you said

I want P53 forever

Only if you don’t function

Mutant in my genome, I can inhibit like

I want you forever

Only if you don’t function

Mutant in my genome, I must proliferate whenever

Am I out of my head?

Am I out of my mind?

If you only knew the pathway I like

Don't think that I can explain it

What can I say, it's complicated

Don't matter what you say

Don't matter what you do

I only wanna proliferate forever

So good, that you can't explain it

What can I say, it's complicated

When you’re inhibited, you can’t work Rb

You try everything, to save me

When something knocks you out

The cell grows free

Keeps proliferating

So constantly

You work forever

When you and phosphates aren’t together

Inactivating transcription regulators, can’t copy DNA wherever, yea,

You work forever

When you and phosphates aren’t together

Inactivating transcription regulators, can’t copy DNA whenever

Am I out of my head?

Am I out of my mind?

If you only knew the bad things I like

Don't think that I can explain it

Suppressor genes say, it's complicated

Don't matter what Rb says

Don't matter what P-five-three do

I only wanna do bad things to you

So good, that APC can't stop it

What can I say, it's complicated